What should be the treatment goal for people living with CHB?

Treatment with antivirals reduces the risk of cirrhosis and HCC, but does not eliminate it9,10

At 5 years of NA treatment:§

Successful treatment is defined by undetectable HBV DNA, normalization of liver enzymes and HBsAg loss.11,12
HBsAg seroclearance is rarely achieved with standard of care13,14

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